Blog Blog Dec 5, 2024 EpicentRx’s Oncolytic Virus-delivered TGFβ Inhibitor, AdAPT-001, Receives FDA Fast Track Designation for Recurrent or Refractory Soft Tissue Sarcoma Treatment AdAPT-001 received Fast Track Designation. So, what, you say? So, let’s dance. Click on the image to... Dec 4, 2024 EpicentRx’s Oncolytic Virus-delivered TGFβ Inhibitor, AdAPT-001, Receives FDA Fast Track Designation for Recurrent or Refractory Soft Tissue Sarcoma Treatment How alright are we about AdAPT-001 Fast Track Designation? Click on the image to play and find out. ... Dec 2, 2024 EpicentRx Word of the Week (WOW): Cozen “My Cozen Vinnie” Cozen Definition (verb): to trick, deceive, or wheedle “He cozened money out of hi... Nov 27, 2024 Make America Late Again “Better late than never” is an oldie but goodie. If we’ve said that line once, we’ve said it 100 tim... Nov 26, 2024 Thanksgiving E-Cards Nov 25, 2024 EpicentRx Word of the Week (WOW): Crassulent “The definition of crassulent is elementary.” Crassulent Definition (adjective): grotesquely obese “... Nov 22, 2024 Friday Funnies: Mind Over Matter Nov 21, 2024 The Artful Blogger The Artful Dodger was an expert thief from Charles Dickens’ novel, Oliver Twist. The Artful Blogger... Nov 20, 2024 Mad, Bad, and Delightful to NO The 19th century Romantic poet, Lord Byron, who died a committed freedom fighter in the Greek War of... Nov 19, 2024 Un-typecastable Sometimes by design and sometimes not, certain actors are cast repeatedly in the same role or play t... Nov 19, 2024 EpicentRx Word of the Week (WOW): Swivel-eyed “Actor and comedian, Marty Feldman (below), from Young Frankenstein was the definition of swivel-eye... Nov 15, 2024 Be Kind, Rewind One of the slogans of Blockbuster Video, the erstwhile video rental store chain from t... Nov 14, 2024 Misfortune Cookie 4 Nov 13, 2024 Fort NOx The United States Bullion Depository in the state of Kentucky, popularly known as “Fort Knox,” is a ... Nov 13, 2024 Misfortune Cookie 3 Nov 12, 2024 Natural-Born Killer We just watched a behind-the scenes docuseries on Netflix called “Countdown: Paul vs. Tyson” ... Nov 12, 2024 Misfortune Cookie 2 Nov 11, 2024 EpicentRx Word of the Week (WOW): Toothsome “Win some, lose some, toothsome.” Toothsome Definition (adjective): 1) attracti... Nov 8, 2024 Misfortune Cookie Nov 8, 2024 Friday Funnies: Racey Humor “Racey Humor” Nov 7, 2024 Fascism The latest F-bomb, a one-size fits all insult, is “fascist.” It is dropped with kneejerk and hyperbo... Nov 6, 2024 If You’re Not First, The Response Will Last One of our favorite quotes from the gleefully stupid film, Talladega Nights: The Ballad of Ricky Bob... Nov 5, 2024 Cancel Culture Sorry Elon Musk, but we unreservedly support cancel culture. Oh yes, we most certainly do. But, keep... Nov 5, 2024 Misfortune Cookie Nov 4, 2024 EpicentRx Word of the Week (WOW): Psephology “The word psephology rocks.” -Pebbles from the Flintstones Psephology Definition (noun): The study o... Nov 1, 2024 Non-Word Salad City We’ve reached peak word salad. 🤞 Much in the news of late, the term, word salad, was originally rese... Oct 31, 2024 Joker The reviews for the much-hyped new movie “Joker Folie à Deux” starring Joaquin Phoenix and Lady Gaga... Oct 30, 2024 Monster Mash In anticipation of Halloween, let’s crank up the volume on the celebrated song “Monster Mash” by Bob... Oct 29, 2024 Halloween E-Cards Oct 28, 2024 EpicentRx Word of the Week (WOW): Confute “If confute does not compute read below.” “You may refute or confute an argument, but you cannot ref... Oct 25, 2024 Friday Funnies: Make America 8 Again “Make America 8 Again” Antiaging is all the “rage.” Oct 24, 2024 (Don’t) Cut It Out According to singer Sheryl Crow (and Cat Stevens), the first cut is the deepest. However, according ... Oct 23, 2024 Who’s Your MDADI? Survival from localized head and neck squamous cell carcinoma (HNSCC) is better than for many cancer... Oct 22, 2024 #Shenanigate Another job title to add to Meaghan Stirn’s already fulsome resume: Chief Shenanigator. (For the rec... Oct 21, 2024 EpicentRx Word of the Week (WOW): Cromulent “This definition of cromulent is perfectly cromulent.” Cromulent Definit... Oct 17, 2024 Methane to the Madness We often write figuratively about climate change since lead EpicentRx therapies, RRx-001 (nibrozeton... Oct 16, 2024 Ozem-pics Ozempic butt. Ozempic tongue. Ozempic fingers. Ozempic burps. Ozempic dreams. Ozempic diarrhea. Ozem... Oct 14, 2024 EpicentRx Word of the Week (WOW): Transduce “Your introduction to transduction below” Transduce Definition (v... Oct 11, 2024 Friday Funnies: Earoma “Earoma” When you smell something while driving and feel the need to turn down the radio to smell it... Oct 10, 2024 Dark Matter AdAPT-001 As we wrote in a previous (and longer) post about RRx-001 (nibrozetone), we idly wondered, after hav... Oct 10, 2024 Dark Matter: RRx-001 (nibrozetone) The intriguing premise of a new Apple TV sci-fi-thriller, Dark Matter, based on a best-selling novel... Oct 9, 2024 No BroZone The United States Adopted Names (USAN) Council and the World Health Organization (WHO) INN Programme... Oct 8, 2024 Put a SOC in It Cisplatin/70 Gy IMRT confirmed as standard of care (SOC) for nonsmoking HPV+ oropharyngeal cancer, w... Oct 7, 2024 EpicentRx Word of the Week (WOW): Traduce “Do not ever traduce the good name of Words of the Week.” “Mrs. Robinson, are you trying to traduce ... Oct 4, 2024 A Second Meeting of the Minds The first meeting of the minds occurred on Saturday, September 28th from 1:30-2:30 pm EST at the 202... Oct 3, 2024 A Solace of Quantum The era of quantum computing is here. But what is quantum computing and how does quantum differ fro... Oct 2, 2024 IP, IP, Hurray Two patents entitled “Methods and Compositions Utilizing RRx-001 for Radioprotection” and “Cytokine ... Oct 1, 2024 Pseudoprogression Seeing is believing, right? Not always in the case of lead EpicentRx therapy, AdAPT-001. In a recent... Sep 30, 2024 Dr. Richard Gordon Presents on RRx-001 at MDS Annual Conference in Philadelphia, PA It was no “Rocky” start for Associate Professor, Dr. Richard Gordon from Queensland, Australia, at t... Sep 30, 2024 EpicentRx Word of the Week (WOW): Valence “What was the emotional valence of the actor, Jack Palance?” Valence Definition (noun): 1) the combi... Sep 27, 2024 Drug Runners They traverse miles and miles of highways and byways, and cross hazardous physical barriers, risking... Sep 26, 2024 Meeting of Da Minds (MDS) All divers require a platform. Accordingly, Dr. Richard Gordon, an Associate Professor from Queensla... Sep 25, 2024 No Favres Some sad news to report. Brett Favre, one of the roughest, toughest quarterbacks to ever put on a fo... Sep 25, 2024 A September to Remember It’s officially Fall, y’all. Fingers crossed that this will be a September to remember for patients ... Sep 23, 2024 EpicentRx Word of the Week (WOW): Demotic “Demotic should be a common word.” “Talk like an Egyptian.” Demotic Definition (adjective): 1) popul... Sep 20, 2024 Boarder Crisis We are in the midst of a “boarder crisis” the likes of which has never been seen before. 😉 Sound fam... Sep 19, 2024 Run, Forest, Run The central lesson from the 1994 Oscar Award-winning movie, “Forrest Gump,” starring Tom Hanks as th... Sep 18, 2024 Off with Their Heads! Symbol of the French revolution, the guillotine, a ruthlessly efficient beheading machine, is in the... Sep 17, 2024 It’s On WOOHOO! It’s on! Heck, yeah, it is! It’s on like freakin’ Donkey Kong. We’re talking about a good ol... Sep 16, 2024 EpicentRx Word of the Week (WOW): Shibboleth “Say shibboleth 5 times in a row if you can.” Shibboleth Definition (noun): custom, tradition, mode ... Sep 13, 2024 Tempus Non-Fugit We’ve all heard the expression “tempus fugit” or “time flies,” which is especially true on vacation ... Sep 12, 2024 Vimeo Killed the Radio Star Too right. In 1979, Buggles, an oversized sunglasses-wearing English band, wrote a prescient and cat... Sep 11, 2024 Nothing To Declare This morning as we sat down in front of the computer to write a blog post and stared at the blank sc... Sep 10, 2024 BD Eyes Beady eyes are round and shiny usually with malice or greed like this. BD eyes are often — but not a... Sep 9, 2024 EpicentRx Word of the Week (WOW): Solecism “It is bad grammer not to know the word solecism.” Solecism Definition (noun): 1) a gram... Sep 6, 2024 A Blog About A Log: Part 2 The log in the title here refers to “logjammed,” a word that means a crowded mass of logs, which blo... Sep 5, 2024 At Symbol Ever stop to consider, as we did this morning for no apparent reason, that the interesting symbol @ ... Sep 4, 2024 Next Jen Here’s our word of the weak, spelling intentional: next gen. This is the cringeworthy, empty phrase ... Sep 3, 2024 EpicentRx Word of the Week (WOW): Prolepsis “In the future, it will help to learn the definition of prolepsis.” Prolepsis Definition (noun): 1) ... Aug 30, 2024 A Blog About A Log: Part 1 The “log” in the title refers to “log phase.” Our use of this term in a strictly mathematical sense ... Aug 29, 2024 At the Speed of Lysis The speed of light, made up of particles called photons, is the fastest in the universe at 186,000 m... Aug 28, 2024 Lost at SCLC Are you lost at SCLC, a complex tumor type with several potential up-and-coming therapies including ... Aug 27, 2024 A Blog About Fog The fog of war. This was a metaphor coined by the Prussian military analyst Carl von Clausewitz in h... Aug 26, 2024 Word of the Woche (WOW): Fingerspitzengefühl “This definition of Fingerspitzengefühl should be at your fingertips.” Fingerspitzengefühl Definitio... Aug 23, 2024 A Pointless Phrase Raise your hand if – like us – you can’t stand the phrase “to your point.” 🙋 No, can’t stand is too ... Aug 22, 2024 Mad, Bad, and Dangerous To Know Part 2 Gulp. Forget Lord Byron. The person perhaps most deserving of the famous epithet “mad, bad, and dang... Aug 21, 2024 Underconsumption Core The latest craze on TikTok with over 31M views is called #underconsumptioncore. This long and unwiel... Aug 20, 2024 Act Your Age! Act your age, young people, and don’t grow up so fast! According to research presented at the Americ... Aug 19, 2024 EpicentRx Word of the Weak (WOW): l’ esprit de l’escalier “It’s not too late to learn about the definition of l’esprit de l’escalier.” l’esprit de l’escalier ... Aug 16, 2024 ICI Hot A long-range forecast from the Climate Prediction Center favors warmer-than-average weather beginnin... Aug 15, 2024 Elevator Pitches Going up? Not if Will Ferrell’s, Buddy the Elf, was on the elevator with you. LOL! Love that scene. ... Aug 14, 2024 Pharmaceutical Breaking Not to be confused with the newly minted Olympic sport of breaking, which featured the instantly mem... Aug 13, 2024 InferNO Per tradition, the Olympic cauldron burns for the duration of the Games until the Closing Ceremony w... Aug 12, 2024 EpicentRx Words of the Week (WOW): Apodictic “An apodictic statement is incontrovertible.” Apodictic Definition (adjective): incontrovertible, ir... Aug 9, 2024 The Torchbearer With the 2024 Olympics now in full swing, we thought to recognize lead EpicentRx therapy, and torchb... Aug 8, 2024 Wisdumb and Wisdumber Jerry Seinfeld recently declared that comedy is dead. Is he right? Maybe. But, hey, why let that sto... Aug 6, 2024 Mad, Chad, and Dangerous To Know On the heels of a previous post entitled “Mad, Bad, and Dangerous To Know”, which was Lady Carolyn L... Aug 5, 2024 EpicentRx Word of the Week (WOW): Callow “If a prequel to Shallow Hal were ever made, when the actor was young and immature, it could be call... Aug 2, 2024 Adpocalypse Now The end, the cataclysmic end, is near (or nigh to use the Biblical term). Extinction—nay, extermina... Aug 1, 2024 Can You Smell What The Rock Is Cooking? The Rock in this case isn’t the ex-professional wrestler and somewhat salacious actor, Dwayne... Jul 31, 2024 Sussudio-progression If Phil Collins, Genesis band member and genius solo songwriter, had also been an oncologist, he mig... Jul 29, 2024 EpicentRx Word of the Weak (WOW): Feckless “If you give a feck, read below.” Feckless Definition (adjective): worthless, weak-in-character, inc... Jul 26, 2024 A Blog About Sm-AH-g Why did we spell “smog” like “sm-AH-g” in the title? Well, if you made it past that first sentence, ... Jul 25, 2024 The Agony of De-Heat This summer across the US the heat is on – really on – both outside and thanks to lead E... Jul 24, 2024 The Flame Game Let’s play not the Blame Game or the Plame Game (which involved the outing of CIA operative Valerie ... Jul 23, 2024 A Blog About Smaug Following on from a previous post called, “A Blog About Smog,” is this one about Smaug, an antagonis... Jul 22, 2024 EpicentRx Word of the Week (WOW): Ecumenical “For a universal definition of ecumenical read below.” Ecumenical Definition (adjective): 1) general... Jul 18, 2024 A Blog About Smog Los Angeles. City of Angels…and smog. In LA, famous for its smog as much as its celebrities and palm... Jul 17, 2024 IO, IO, It’s Off To Work We Go The IO from the title stands for immune-oncology. This term, IO, refers to therapies that mobilize t... Jul 16, 2024 A Blawg About a Dawg Why is the word “blog” spelled like “blawg” in the title? For the Aw! factor. Dogs, or rather, dawgs... Jul 15, 2024 EpicentRx Word of the Week (WOW): Longueur “Hopefully this post is short enough not to contain longueurs.” Longueur Definition (noun): a long, ... Jul 12, 2024 Divert Shields! The following is excerpted from a WebEx that EpicentRx gave in January. “Divert shields!” is a commo... Jul 11, 2024 TGF-β Mayhem Move over, Dean Winters, the good actor who plays the part of the disaster-prone Mayhem mascot in th... Jul 10, 2024 TGF-β, the Architect of Disaster The most heavily fortified and militarized border in the world isn’t the one between North and South... Jul 9, 2024 Magic 8 Ball, Marijuana Use, and Head and Neck Cancer We asked the all-knowing, all-seeing Magic 8-ball – you know the plastic sphere shaped like an... Jul 8, 2024 EpicentRx Word of the Meek (WOM): Longanimity “Be patient with this definition of longanimity.” Longanimity Definition (noun): patient forbearance... Jul 3, 2024 How To Curse Like An Oncologist Swear like a sailor, a stevedore, a fishmonger, a termagant, or a trooper? If you must. After all, a... Jul 2, 2024 Enter the Epicenter Along with “Remission Possible,” one of the new taglines on the redesigned EpicentRx website is “Ent... Jul 1, 2024 EpicentRx Word of the Week (WOW): Eristic “There’s no controversy about the definition of eristic.” Eristic Definition (adjective): pertaining... Jun 28, 2024 The Write Stuff Blogitamus, ergo sumus. We blog; therefore, we are. Or blogitamus, ergo hummus. We blog; therefore, ... Jun 27, 2024 The Eye of Sauron? For those who think that the beloved Lord of the Rings (LOTR) trilogy by JRR Tolkien is a work of pu... Jun 26, 2024 We Spy with Our Imaging Eye Show of hands, who remembers the children’s game, I Spy? (Time for an obligatory ‘80s reference: Any... Jun 25, 2024 Sun’s Out Guns Out Summer is officially here, and so is the gun show. Not talking about Sean Astin, who plays Drew Barr... Jun 24, 2024 Cold As Ice A fantastic, and seriously catchy song from ‘80s British-American rock supergroup Foreigner is, R... Jun 24, 2024 EpicentRx Word of the Week (WOW): Hebdomadal “Hebdomadal is a literal word of the week.” Hebdomadal Definition... Jun 21, 2024 Fahrenheit 104.51 The esteemed science fiction author, Ray Bradbury, who died in 2012, claimed, perhaps erroneously, a... Jun 20, 2024 But Wait, There’s More! On a crossword puzzle, we came across this 5-letter clue: “But wait! There’s more!” The answer... Jun 18, 2024 KEVLARx: Hit Me With Your Best Shot We have officially designated Pat Benatar’s 1980s take-no-prisoners smash single Hit Me With Your Be... Jun 17, 2024 EpicentRx Word of the Weak (WOW): Epicene “We’re neutral about the word epicene.” Epicene Definition (adjective): 1) weak, flaccid... Jun 14, 2024 Mad, Dad, and Dangerous To Know This is the third post we’ve written that riffs on Lady Carolyn Lamb’s awesome, reputation-defining ... Jun 13, 2024 Mr. Best One of the most successful YouTube icons or self-styled “influencers” of all time is Jimmy Donaldson... Jun 13, 2024 Flood-gates We live not in an age of walls but of gates. Ever since the “Watergate” break-in over 50 years ago, ... Jun 12, 2024 Pink Stripes After writing one of our absolute favorite blog posts (here), on Tom Brady, Bill Belichick, Robert K... Jun 11, 2024 EpicentRx Word of the Weak (WOW): Effete “The thrill of victory, the agony of effete.” Effete Definition (adjective): 1) degenera... Jun 10, 2024 Fox News You’re entering the Spin City Zone! We wish accomplished actor, caring philanthropist, and genuine i... Jun 7, 2024 The Pecking Order of TGF-β How unintentionally ironic that the phrase “winner, winner, chicken dinner!” is used to celebrate a ... Jun 6, 2024 The Number One Impersonator Maybe the second-best impersonator that we’ve ever seen is Frank Caliendo, who sounds like a dead ri... Jun 5, 2024 The Rainmaker The Merriam-Webster online dictionary defines a rainmaker as 1. “a person who produces or attempts t... Jun 4, 2024 Mostly Single and Ready to Mingle At #BIO2024, the Pharmaceutical Industry’s answer to speed dating, EpicentRx declares its relationsh... Jun 3, 2024 EpicentRx Word of the Week (WoW): Plenary “Read this definition of plenary that is complete in every way.” Plenary Definition (nou... May 31, 2024 Making Sarcoma History The MD Anderson tagline is “Making Cancer History”, which applies to sarcoma investigator and MD And... May 31, 2024 BIOTinder Profiles May 31, 2024 B-IO+ 2024 BIO, which stands for Biotechnology Innovation Organization, is a signature biotech partnering confe... May 30, 2024 Disrupt Or Go Home The term, disruptive innovation, reminds us of what the late, great funnyman and real disruptive inn... May 29, 2024 Here Comes the ASCO Boom “BOOM!” emailed Dr. Anthony P. Conley to us after having received notice that he was selected... May 29, 2024 ASCO Challenge It is a real challenge to get an abstract accepted at ASCO, so this week in the lead-up to the big c... May 28, 2024 Blogging About Vlogging Captain’s blog Stardate 5/28/2024 We’ve officially taken the plunge and launched a YouTube channel d... May 28, 2024 EpicentRx Phrase of the Week: Disruptive Innovation “Innovaaaation is making us great.” Sung to the tune of the Heinz “Anticipaaaation” ketchup co... May 24, 2024 Dr. Anthony P. Conley To Give Prestigious Oral Presentation on AdAPT-001 at ASCO 2024 Just exactly how prestigious is it to be selected for an Oral Presentation at the American Society f... May 22, 2024 Brady or Belichick? It is a question for the ages – and a long-running debate, which we hope to settle once and fo... May 21, 2024 It’s Hip To Be Square Chemical rings come in several different shapes. Triangle-shaped 3-membered rings like cyclopropane.... May 20, 2024 EpicentRx Word of the Week: Munchausen “Munchausen puts the “con” in hypochondria.” Munchausen’s Syndrome noun moon-chau-zn sihn-droo... May 17, 2024 ASCO and BIO 2024 Preview This preview is rated BD for Business Development. It’s almost showtime! The stage is set for the Ju... May 16, 2024 A Bug and A Drug If you, like Huey Lewis memorably sang in 1987, want a new drug… One that won’t make me ... May 15, 2024 “Mad, Bad, and Dangerous to Know” So said Lady Carolyn Lamb about her lover, the Romantic poet, aristocrat, infamous lady killer, and ... May 14, 2024 You Can’t Teach An Old Dogma New Tricks Or can you? This phrase, which comes from the legendary writer, Dorothy Parker, best known for her w... May 13, 2024 EpicentRx Word of the Week (WOW): Diegesis “Is it called ‘indiegesistion’ when we hear upset stomach noises in a movie or on the TV... May 10, 2024 Bullet Blog #5: 4 Before and Then No More Celebrated American short-story writer and poet, Edgar Allan Poe, famously wrote, “Quoth the Raven &... May 9, 2024 Bullet Blog #4: Fast Facts About Cisplatin First described by the Italian chemist Michele Peyrone in 1845, cisplatin is an alkylating agent tha... May 8, 2024 Bullet Blog #3: Fast Facts About Kevlar ® The Phase 2b clinical trial with RRx-001 (nibrozetone) against chemotherapy and radiation-induced se... May 7, 2024 Bullet Blog #2: Mouth or Mowth How do you spell mouth? As above, right? Yes, unless you develop severe oral mucositis (SOM) from th... May 6, 2024 Bullet Blog #1: Welcome Aboard the KEVLARx Bullet Train The KEVLARx Bullet Train has finally left the station. Tickets please. Final destination: head-and-n... May 6, 2024 EpicentRx Word of the Week (WOW): Distaff “Distaff? What about datstaff?” Distaff Definition (noun): a stick aroun... May 3, 2024 The KEVLARx Bullet Train All aboard the KEVLARx bullet train! Destination: head and neck cancer (HNC) without a stop, hopeful... May 3, 2024 A Blog About Blag A British slang word (you know how we absolutely love the Brits – that’s true AE), which may d... May 2, 2024 Nrf2 Herder Happy early “May the 4th Be With You” aka #StarWarsDay. If fans of Star Trek are called Trekkies, or... May 2, 2024 Danger Close In artillery and naval gunfire support, the term “danger close” indicates proximity to an intended t... Apr 30, 2024 Lyse! LICE! Ugh! #Gross! #Disgusting! #Horrible! Or, dare we say it, #lousy! For most parents a plague of ... Apr 29, 2024 EpicentRx Word of the Week: Retcon “Because the TV show, The Conners, retconned the past of the original show, Rosanne, so many times i... Apr 25, 2024 Rocky Road Most. Decadent. Ice. Cream. Ever. Rocky Road brings together the best of several worlds: creamy choc... Apr 24, 2024 Lost Time Is Never Found Again Poor Richard’s Almanac was an annual compendium of pithy proverbs and prognostications written and p... Apr 23, 2024 EpicentRx Word of the Week: Eustress “I stress. You stress. We all scream for eustress.” Eustress Definition ... Apr 22, 2024 Say Yes to Eustress “Wound up,” “stressed out,” “burned out,” “tied up in knots,” “on pins and needles,” “on eggshells,”... Apr 18, 2024 The Great Debate Here is our list for the top 10 Greatest Debates in history (feel free to weigh in): 1. Creation vs.... Apr 17, 2024 Hot or Not? From time to time in this space, we will apply the phrase “Hot or Not?” to tumors from cases that we... Apr 16, 2024 SARC: Defiance Through Alliance Not too long ago, we met Steve Young. Not the Steve Young, mind you, the Hall of Famer who qu... Apr 15, 2024 The Taxman Tax evasion is much in the news of late. Penalties for it are harsh and may include fines or, impris... Apr 15, 2024 EpicentRx Word of the Week: Nosism “Don’t turn up your nose at Nosism.” Nosism noun NO-siz-em Definition: to refer to oneself as ... Apr 12, 2024 En Fuego in San Diego At the AACR conference in San Diego, Drs. Tony Reid, CEO of EpicentRx, and Anthony P. Conley, a sarc... Apr 11, 2024 A Total Eclipse of the Heart Here is a cardiopharmaceutical take on the recent eclipse, which started in Mexico and moved northea... Apr 11, 2024 Mechanism X Factor Much ink/many electrons have been spilled to explain the admittedly complex mechanisms of action for... Apr 10, 2024 MMAdAPT-001 Modern day gladiators, the best mixed martial artists (MMAers) like Khabib Nurmagomedov, Jon Jones, ... Apr 9, 2024 Anti-Inflammaging: A Modern-Day Fountain of Youth By: Bryan Oronsky, Ahad Javansalehi “Who wants to live forever?” -Freddie Mercury Introduction A com... Apr 8, 2024 EpicentRx Word of the Week: Aesculapian “Aesculapian, heal thyself.” The caduceus (left) vs. the Rod of Aesculapius (right) Aesculapian adje... Apr 5, 2024 Care-ismatic If we were to describe Dr. Tony Reid, CEO, and founder of EpicentRx, whip-smart Professor Emeritus o... Apr 4, 2024 Nobody Does it Beta From the Spy who Loved me, Carly Simon sang what is, bar none, in our humble opinion, the greatest J... Apr 3, 2024 Way Faster and Much More Furious By the time you’ve read this sentence, we imagine that another Fast & Furious sequel starring Vi... Apr 2, 2024 Show and Tell One of the most earnestly endearing collection of essays ever written is entitled, “All I Really Nee... Apr 1, 2024 What a Joke! AdAPT-001 floats into a bar, encased in a cationic liposome, and orders a thimble of whisky, which i... Apr 1, 2024 EpicentRx Word of the Week: Quisling “What do you call a Panda that betrays its own kind?” “A Quis-Ling Ling”. “What did Beyo... Apr 1, 2024 EpicentRx To Attend the American Physiology Summit (APS) No per-APS about it. EpicentRx is a definite for the American Physiology Summit (APS) from April 4-7... Mar 28, 2024 X Marks the Not RRx-001 is a very versatile small molecule. Clinically, it is used as an anticancer, anti-mucositis,... Mar 27, 2024 Protect and Swerve “To Protect and to Serve” was the former motto of the Los Angeles Police Department. “To Protect and... Mar 26, 2024 Pop Goes the Bubble Pop. This is the sound of bubbles bursting throughout history. Tulipmania (1634-1638) in Holland. Po... Mar 25, 2024 EpicentRx Word of the Week: Forme Fruste “Below is a hopefully not incomplete definition of the term, forme fruste”. Forme Fruste noun fawm f... Mar 22, 2024 Face It – Part 1 The other day someone jokingly called EpicentRx a two-faced company – because we have 2 lead t... Mar 22, 2024 A Real Gem Pharmaceutical companies frequently boast about the “crown jewel(s)”, which refers to their most pri... Mar 21, 2024 The Big Bad Wolf of Treatment Related Toxicities Who’s afraid of the Big Bad Wolf? Literally, everyone, especially when the Big Bad Wolf symbolizes t... Mar 20, 2024 Should I Stay or Should I Go Now? In case, like us, you happened to wake up one morning and randomly wonder who or what the timeless r... Mar 19, 2024 Zoom-itis As the COVID-19 threat seemingly fades, a new and much more insidious pandemic has arisen to take it... Mar 18, 2024 EpicentRx Word of the Week: Anfractuous Anfractuous adjective an-FRACK-choo-uhss Definition : twisty, winding, bendy, convoluted, tortuous. ... Mar 15, 2024 Blogging About Hogging Not to be pedantic or a “boar”, but in these weekly blog posts we practice nosism aka “we-ism”, whic... Mar 15, 2024 EpicentRx Hollywood Squares On a recent team-wide Zoom call, Meaghan Stirn, VP of Special Projects, which is a nefariously myste... Mar 14, 2024 Mostly Medical Knock Knock 1. Knock, knock Who’s there? W.H.O. Who’s W.H.O? The World Health Organization. 2. Knock, kno... Mar 13, 2024 TGF-β Gate In the wake of #KateGate, #Katespiracy, #FakeKate, and #WhereIsKate, owing to the mysterious monthsl... Mar 13, 2024 “The First Rule of Fight Club Is…” As any true fan of the Brad Pitt and Edward Norton movie based on the Chuck Palahniuk novel of the s... Mar 13, 2024 Team Possible In honor of International Women’s Day, which occurred last Friday March 8th, we recognize and applau... Mar 12, 2024 The Road House Rules of RRx-001 (Nibrozetone) and AdAPT-001 A remake of the 1989 unapologetically over-the-top cult classic, “Road House”, is set to drop on Ama... Mar 11, 2024 Ask EpicentRx™ “A real brew-haha”. Q: “I’ve been having trouble getting to sleep this week and getting up for work ... Mar 11, 2024 EpicentRx Word of the Week: Struwwelpeter “Struwweleinstein”. Strewwelpeter noun STROO-uhl-pee-tuhr Definition: : tousle-head Example sentence... Mar 8, 2024 Remission Possible Hello, dear reader. Your mission, should you decide to accept it, is to check out our new website de... Mar 8, 2024 DST-itis Get ready to spring forward – one day later. This year Daylight Saving Time (DST) returns on M... Mar 6, 2024 The Story Behind Cancer Awareness Ribbons The year was 1979. Jimmy Carter was president. Tensions ran high. Gasoline was in short supply. Cars... Mar 5, 2024 Neither Fish Nor Fowl An advocacy organization that we spoke to last month characterized themselves as “neither fish nor f... Mar 4, 2024 EpicentRx Word of the Week: Banausic “It is never banausic to read the Word of the Week”. Banausic adjective buh-naw-sik Definition: : co... Mar 1, 2024 A Blog About a Blog About a Blog Not to brag but what an absolutely meta-tastic title this is! Also a metastatic one because of the n... Mar 1, 2024 Easy as P.I.E. For tumors, unfortunately, to not only survive but also thrive is often as easy as p.i.e.—those lett... Feb 29, 2024 A Look Before the Leap February 2024 is a leap year, meaning that an extra day is tacked on to the end of the shortest mont... Feb 28, 2024 The Posts with the Mosts Our by-the-numbers PR firm, MCS, has provided us with up-to-date analytics on the EpicentRx website.... Feb 27, 2024 Jumping the Couch We met someone the other day who asked us to rate how enthusiastic we are about lead EpicentRx thera... Feb 26, 2024 EpicentRx Word of the Week: Chthonic “Chthonic rhymes with demonic, which is a sort of synonym”. Chthonic adjective thon-ik Definition: :... Feb 23, 2024 A Blog About A Blog Chuckle. What a meta (self-referential) title—and image. So, this morning, having woken up way too e... Feb 22, 2024 The Matrix REPLATINUM: RRx-001 (Nibrozetone) and Platinum-resistant SCLC Inevitably, at some point during their progression, small cell lung cancer (SCLC) tumors learn to do... Feb 21, 2024 ‘Tis the Season for Treason The biggest traitor in human history is not Judas Iscariot, Benedict Arnold, Guy Fawkes, Vidkun Quis... Feb 20, 2024 A Bittersweet EpicentRx Story What is the most addictive drug in the universe? If you ask us (and some others especially post Vale... Feb 19, 2024 EpicentRx Word of the Week: Caliginous “You dare to come to me for a heart, do you? You clinking, clanking, clattering collection of caligi... Feb 16, 2024 Measure 12 Times and Cut Once The expression, measure twice, cut once (or, more humorously, measure once, cuss twice), means that ... Feb 15, 2024 It’s Both a Floor Wax AND a Dessert Topping So said zany spokesman, Chevy Chase, in an equally zany Saturday Night Live (SNL) skit from the 1970... Feb 14, 2024 Love and Hate Relationship This Valentine’s Day what better subject to tackle than love and hate, specifically as it applies to... Feb 12, 2024 EpicentRx Word of the Week: Fuliginous “Hopefully this definition of fuliginous ‘soots’ you.” Fuliginous adjective fyoo-LIJ-uh-nus fuligino... Feb 9, 2024 Big News About Alzheimer’s Disease A Viagra a day keeps the neurologist away? This is the suggestion from a retrospective study from th... Feb 8, 2024 The Royal Wee The recent disclosure of King Charles’ cancer diagnosis has touched off a frenzy of media speculatio... Feb 5, 2024 EpicentRx Word of the Week: Uliginous “The definition of uliginous is as clear as mud.” Uliginous adjective yoo-LIJ-uh-nus Definition: : s... Feb 2, 2024 G-Men True we don’t carry an FBI badge like the facsimile of the one pictured above, but feel free to call... Jan 29, 2024 EpicentRx Word of the Week: Gnathonic “To be gnathonic is also to be somewhat ironic.” &n... Jan 26, 2024 23andMe Results for RRx-001 (nibrozetone) If the hybrid and “diverse” small molecule, RRx-001 (nibrozetone) could spit in a vial and ship it o... Jan 26, 2024 23andMe Results for AdAPT-001 If the “smart” oncolytic adenovirus, AdAPT-001, assuming it really was that smart, could spit in a v... Jan 24, 2024 Blogging about Leapfrogging To leapfrog is to improve position by means of vaulting. In drug development it is vaunted to be vau... Jan 22, 2024 EpicentRx Word of the Week: Epigone “EpicentRx is always iconic, usually harmonic, rarely ironic, and never ever epigonic.” “Epihere tod... Jan 19, 2024 A Blog About a Bog The American Heritage Dictionary defines a bog as “an area of soft, naturally waterlogged ground.” B... Jan 17, 2024 Bigger is Worser Go big or go home. Live large. Think big. Hit the bigtime. In general, we are conditioned to think t... Jan 16, 2024 In the Cards The two most advanced indications for RRx-001 (nibrozetone) are in oncology as a chemosensitizer for... Jan 15, 2024 EpicentRx Word of the Week: Aporia “What’s the storia with aporia?” “Don’t be in doubt about the meaning of aporia.” Aporia noun uh-poo... Jan 12, 2024 Blogging About Clogging This is a companion post to a recently written one entitled, “Blogging About NO Clogging.” That post... Jan 12, 2024 Blogging About NO Clogging Time and again in conditions like myocardial infarction, hemorrhagic/hypovolemic shock, stroke, pulm...
