Mechanism X Factor

Apr 11, 2024

Much ink/many electrons have been spilled to explain the admittedly complex mechanisms of action for the small molecule, RRx-001 (nibrozetone). Applicable words and phrases are “NLRP3 inhibition,” “Nrf2 agonism,” “NO donation,” and “vascular normalization.” A more succinct description is shown below, as RRx-001 transfers its “x.”

Le voilà.