EpicentRx Word of the Week: Inflammaging

Dec 11, 2023

“Inflammaging is highly dam-aging, which makes it disadvant-aging. By contrast, anti-inflammaging is salv-aging.”

Inflammaging or Inflammageing‎ (noun)



: an age-related increase in systemic chronic inflammation.

Example sentences:

Inflammageing, defined as an age-related increase in the levels of pro-inflammatory markers in blood and tissues, is a strong risk factor for multiple diseases that are highly prevalent and frequent causes of disability in elderly individuals…” From Ferrucci L, Fabbri E. Inflammageing: chronic inflammation in ageing, cardiovascular disease, and frailty. Nat Rev Cardiol. 2018 Sep;15(9):505-522.

“The antonym of inflammaging is anti-inflammaging. The former is harmful, the latter is beneficial.”


The lead EpicentRx small molecule, RRx-001 (nibrozetone), may prevent or reduce inflammaging.

About the Word:

Blend of the two words inflammation and aging