Blogging About Pettifogging

Jan 10, 2024

Call it pettifogging, captious carping, or just plain ol’ nitpicking, but we really hate it when spell check rewrites RRx-001 as “RRX-001” or “RRex-001.” Not that we need any justification, but Rx (not RX or Rex) means prescription or recipe, and plus RRx-001 is a small molecule, not a large one, which are all reasons spell it with a little “x” minus the “e.”

Having received the International Nonproprietary Name (INN) nibrozetone (pronunciation: NA-ih-broh-tseh-TOH-uun) for RRx-001 we now usually try to write it that way, which avoids any headache or contretemps.

The same problem occurs with EpicentRx, which for some reason our spell check, given its druthers, will “correct” to EpicentRX or sometimes even to “EpicentRex.”

Ditto with “tx” medical shorthand for treatment or therapy, which, being doctors, we use all the time and which spell check in its infinite wisdom (sarcasm most definitely intended) sometimes corrects to “TX,” an abbreviation for Texas.

Now to be clear we absolutely love Texas, especially MD Anderson in Houston with which we have a great relationship (see blog post In Dr. Conley We Trust from October of 2023) through our clinical work together on the EpicentRx lead oncolytic virus, AdAPT-001. However, having already established our penchant for pettifoggery, we point out that EpicentRx, not EpicentRX or EpicentRex, is headquartered in CA (California), not TX.

Not that it really matters anymore since we permanently disabled the spell check function on our Macs—sometimes previously written as Max.